The Wincom Tablet Dissolution Tester is a high-performance pharmaceutical testing instrument designed to determine the precise rate and extent at which active pharmaceutical ingredients (APIs) dissolve from solid dosage forms like tablets and capsules into a liquid medium. Operating in strict compliance with international pharmacopoeia standards (including USP, EP, and BP), it provides a highly controlled, temperature-regulated, and uniform agitation environment. This instrument is vital for evaluating bioavailability, drug release profiles, and ensuring batch-to-batch consistency in pharmaceutical manufacturing and research laboratories.

Technical Specifications

• Number of Vessels: Available in 3, 6, or 8 vessel configurations (depending on the specific model)

• Stirring Speed Range: 20 RPM to 200 RPM

• Stirring Speed Accuracy: +/- 4 percent of set speed (or +/- 1 RPM)

• Temperature Control Range: Ambient temperature to 45.0 degrees Celsius

• Temperature Control Accuracy: +/- 0.3 degrees Celsius

• Paddle and Basket Wobble Range: Less than or equal to 0.5 mm

• Testing Methods Supported: USP Method 1 (Baskets) and USP Method 2 (Paddles)

• Vessel Capacity: Standard 1000 mL clear glass dissolution vessels

• Power Supply: AC 220V, 50Hz

Key Features

• Full Pharmacopoeia Compliance: The geometric dimensions, tolerances, and mechanical alignments of the paddles, baskets, and vessels are precision-crafted to perfectly match USP/EP/BP standards.

• Advanced Water Bath Circulation: Built with an integrated magnetic water pump and high-efficiency heating system that continuously circulates water throughout the bath, maintaining a highly uniform temperature profile across all vessels.

• Motorized Head Lift Mechanism: Features an automatic or smooth manual motorized lift design that raises and lowers the upper drive head seamlessly, making it easy to change paddles or clean vessels.

• High-Grade Material Construction: All parts that come into contact with the dissolution media—such as the paddles, basket shafts, and sinkers—are manufactured from premium, chemical-resistant SUS316L stainless steel.

• Intelligent Digital Console: Equipped with a clear LCD/LED display screen that allows real-time tracking of parameters, including rotation speeds, system temperature, and countdown timers.

Primary Applications

• Pharmaceutical Quality Control: Performing routine dissolution testing on production batches to verify drug release compliance before products are released to the market.

• Drug Formulation and R&D: Developing new drug delivery systems and analyzing how changes in excipients or compression forces affect the dissolution rate.

• Bioequivalence and Generics Testing: Conducting comparative dissolution profiling to establish bioequivalence between generic drug formulations and reference listed drugs (RLDs).